IGFBP-3, insulin-like growth factor binding protein-3
In 2022, sales of Jynarque totaled 139.41 billion JPY ($1.06 billion USD), up 38.9 percent from 2021
These supplements are carefully formulated to assist in your body's natural processes, enhancing your ability to maintain balanced blood sugar levels and a healthy weight.* Our supplements that increase GLP-1 are particularly beneficial for those undergoing care that require precise metabolic control

2.4% placebo SURMOUNT-1 weight loss / up to 22.5% mean reduction at 72 weeks with tirzepatide 15 mg HbA1c in normoglycemic participants / dropped 0.2 to 0.5 percentage points in major GLP-1 trials SELECT cardiovascular benefit / 20% reduction in MACE with semaglutide 2.4 mg over 3.4 years median follow-up SCALE Obesity and Prediabetes / liraglutide 3.0 mg reduced new-onset type 2 diabetes by 79% over 3 years in prediabetic participants Fasting insulin reduction / 20 to 40% decreases observed across STEP and SURMOUNT programs Current ADA guidance / pharmacotherapy recommended as adjunct to lifestyle for adults with obesity What "Before Prediabetes" Actually Means A person can carry significant metabolic risk without meeting the laboratory cutoffs for prediabetes (fasting glucose 100 to 125 mg/dL or HbA1c 5.7% to 6.4%)
While semaglutide is effective for managing diabetes and aiding weight loss, its potential effects on skin health should not be overlooked
Goals Improve body composition Boost metabolic function Support consistent, sustainable weight loss Increase energy and motivation Treatmentable Areas Busy professionals, post-baby glow-getters, and anyone ready to ditch yo-yo dieting in favor of real, lasting change