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Ongoing cortisol can blunt satiety hormones like GLP-1, so it is harder to feel satisfied

Blood was collected in EDTA-coated microvette tubes, chilled on ice and centrifuged at 3,000 g and 4 C for 10 min

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This rapid expansion in use (with nearly 12% of Americans now having tried GLP-1 medications) has brought with it concerning reports of severe side effects that manufacturers allegedly failed to adequately disclose, forming the basis of thousands of lawsuits now consolidated in federal court