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In humans, its established as a selective GH secretagogue 9 with minimal off-target hormone effects even at doses far above the effective GH dose

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Damaged mitochondria release molecules that activate the NLRP3 inflammasome, a protein complex that amplifies inflammatory cytokine production

[DOI] [PMC free article] [PubMed] [Google Scholar] 246.van der Meer AJ, Veldt BJ, Feld JJ, Wedemeyer H, Dufour JF, Lammert F, Duarte-Rojo A, Heathcote EJ, Manns MP, Kuske L, et al