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If your chronic fatigue seems to get better only with adenosyl B12 (and not with methyl B12), its possible that you have some rare condition preventing your body from the inter-conversion

People start a new compound on Monday and step on the scale on Friday expecting transformation

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So there has been a lot of back and forth on this

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It exhibits antioxidant activity due to its ability to combine with peroxyl radicals before they propagate peroxidation to lipids