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But its stimulation of melanocyte proliferation raises theoretical concerns, and case reports of melanoma in users have been published

Aertsen A, Meersman F, Hendrickx MEG, Vogel RF, Michiels CW (2009) Biotechnology under high pressure: applications and implications

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Impact of hormone replacement therapy on risk of ovarian cancer in postmenopausal women with de novo endometriosis or a history of endometriosis