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Who should NOT take phentermine Phentermine is contraindicated in patients with: Cardiovascular disease including coronary artery disease, prior heart attack, stroke, arrhythmias, congestive heart failure, or uncontrolled hypertension Hyperthyroidism (overactive thyroid) Glaucoma Agitated states or history of drug abuse Pregnancy or breastfeeding MAO inhibitor use phentermine must not be taken within 14 days of stopping an MAO inhibitor medication Hypersensitivity to sympathomimetic amines Severe renal impairment dose reduction to 15mg daily is required for patients with eGFR 1529 mL/min/1.73m Your prescriber will review your full medical history, current medications, blood pressure, and cardiovascular risk before prescribing phentermine

MedComm 2(4):73055 Chaouhan HS, Vinod C, Mahapatra N et al (2022) Necroptosis: a pathogenic negotiator in human diseases

Deep Systemic Anti-Inflammation: Researchers observe highly effective modulation of inflammatory cytokines, calming systemic inflammation at a cellular level

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Although mitochondrial respiration was noted as unchanged in resting and stimulated CD4+ and CD8+ T cells, CD8+ T cells were found to have a reduction in proton leak, ATP synthesis, and mitochondrial membrane potential (254)