NAD+ works as a co-substrate for several enzyme families: Sirtuins (SIRTs) : These NAD+-dependent deacetylases remove acetyl groups from proteins, including histones that affect gene expression and cellular function
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Pierluigi R, Antonio G, Giovanni G, Rossella CJFPH
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In addition to its antitumor effects, Salviolone has anti-inflammatory and antioxidative stress effects and has been shown to have antifibrotic effects by reducing the levels of fibrosis-related markers such as fibronectin and collagen IV [44, 45]
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