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Tirzepatide simultaneously stimulates GIP and GLP-1 receptors, which increases general insulin sensitivity, leading to improved glycemic control and better weight loss compared to GLP-1-RAs (36)

Pharmacists in primary and secondary care play an important role in supporting safe transitions, such as assessing indication, dosing, monitoring and patient education

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They work by slowing digestion, reducing appetite, and helping regulate blood sugar

The medication's unique dual incretin activity distinguishes it from single-receptor GLP-1 agonists and contributes to its enhanced efficacy profile