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This molecule consists of two components bound together

The intestinal epithelial layer plays an essential role in separating luminal components, including microbes and dietary components, from systemic circulation to limit their interaction with the subepithelial immune system (Luissint et al

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ATGL will be referred to by its official gene symbol PNPLA2 throughout the rest of this review to note its similarity with other PNPLA paralogs