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2013;8(6): e63776

Nodules or lumps: Injection creating small subcutaneous deposits

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doi: 10.1158/2159-8290.cd-17-1461 14 PerilloBDi DonatoMPezoneADi ZazzoEGiovannelliPGalassoGet al

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Morphologically, the mitochondria are smaller with an increase in mitochondrial membrane density and reduction or disappearance of mitochondrial cristae as well as rupture of the outer mitochondrial membrane, but the nuclear size is intact ( c -glutathione (GSH)glutathione peroxidase 4 (GPX4) axis, the elevation of iron metabolism axis, and the lipid metabolism (Figure 1)