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Who Should Not Use These Compounds and What Are the Key Risks Neither retatrutide nor tirzepatide is appropriate for individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 (MEN 2), based on preclinical signals observed across the GLP-1 receptor agonist class

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Li J, Wang B, Luo Y, Bian Y, Wang R

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