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Assessing the Efficacy and Safety of Multiple Drugs for IBS-C: A Systematic Review and Network Meta-Analysis

Generic semaglutide is not expected until at least 2031 to 2033, based on current patent expiration timelines

Patients typically begin with one tablet daily and increase weekly until reaching the full treatment dose

Its safety profile is generally consistent with other GLP-1-based therapies, with common side effects including nausea, diarrhea, and decreased appetite

The combination of weight loss and improved insulin sensitivity addresses the core drivers of type 2 diabetes development