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Across the cagrilintide clinical program, the dominant tolerability issues have been gastrointestinal: nausea, reduced appetite, constipation, and, less commonly, vomiting a profile shared with pramlintide and with GLP-1 agonists, and mechanistically expected from a compound that slows the stomach and engages the area postrema

Ferdowsian HR, Levin S

Epub 2021 Jun 26

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It is ideal to combine it with exercise and a well-balanced diet

Beta sheets: These are formed when a polypeptide chain folds back on itself, creating a loop structure