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The KPMP study is approved by the University of Washington Institutional Review Board (IRB 20190213)

Patients with certain genetic profiles may benefit more from semaglutide alone, while others achieve superior results by pairing it with tirzepatide through PlexusDx's GLP-Squared formulations

doi: 10.3109/03009749409103030 185 KosinskaMKLiebischGLochnitGWilhelmJKleinHKaesserUet al

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A study involving children and adolescents with obesity found that non-responders (defined as subjects whose BMI z-score was maintained or increased) to nutritional or exercise regimens had significantly increased choline and a decreased B/C ratio after 6 months