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Findings from Phase 1 trials helped refine patient selection criteria for later trials, ensuring appropriate study populations

Genetic factors also play a rolevariants in genes like GLP1R and GIPR influence individual sensitivity to the medication

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Storage of red blood cells in alkaline PAGGGM improves metabolism but has no effect on recovery after transfusion

Maintenance dosage: Clinical trials have studied maintenance doses of 4 mg, 9 mg, and 12 mg once weekly

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