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795 Platelets release mitochondria, which are related to bacteria in composition, when activated either in microparticles or free into plasma, where they associate with neutrophils and the platelet enzyme PLA2 IIA, which hydrolyzes mitochondrial and bacterial membranes, releasing a variety of proinflammatory molecules, including mitochondrial DNA, arachidonic acid, and lysophospholipids that are themselves capable of initiating NET formation

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Acid-degradable core-shell nanoparticles for reversed tamoxifen-resistance in breast cancer by silencing manganese superoxide dismutase (MnSOD)

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Comprehensive metabolome analyses reveal N-acetylcysteine-responsive accumulation of kynurenine in systemic lupus erythematosus: implications for activation of the mechanistic target of rapamycin