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10 In mice, microglia arise from a population of yolk sacderived macrophages generated during primitive haematopoiesis, which begin migrating into the neuroepithelium at embryonic day 8.5

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Rat MCL and Achilles tendon models are informative but do not guarantee equivalent results in humans

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Studies in both normal healing and delayed healing models have shown improvements in callus volume, mineralization, bone mineral content, rate of successful union, and mechanical strength at fracture sites