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GPX1 affects the effects of the major factors involved in both macro and micronutrient metabolism by regulating gene expression, protein function, and enzyme activities [59, 60, 61]

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Two reactions involving glucose metabolites catalyse the reduction of NADP+ to NADPH: glucose 6-phosphate dehydrogenase, forming 6-phosphogluconate, and phosphogluconate dehydrogenase, which yields the 5-carbon sugar ribulose 5-phosphate, liberating carbon dioxide from carbon-1 of the substrate

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