As GLP-1 receptor agonists (GLP-1s) like semaglutide (Wegovy, Ozempic) and tirzepatide (Mounjaro, Zepbound) become increasingly common in the treatment of diabetes, obesity, and cardiovascular disease, retina specialists are paying close attention to whether the drug therapies may influence ocular disease in already high-risk patients
Peptides like Retatrutide can lose potency if left at room temperature for extended time periods
"A young man escalated his dose of retatrutide, he experienced secretory diarrhoea, which was very severe, and he was admitted to hospital requiring a lot of intravenous fluid rehydration," Dr Holt said
For 20mg vials used during maintenance dosing, 1.0mL of bacteriostatic water is optimal
Vilsbll T, et al
In that case, it will be considered cost-effective and preferable treatment compared to other GLP-1R agonists and antidiabetic drugs [123]