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Hopkins was also the first to identify the constituent amino acids of GSH in 1929 and was corroborated independently by Edward Calvin Kendall

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Experimental data indicate increased functional tone of the lower esophageal and pyloric sphincters following peptide administration, a response associated with reduced reflux-related injury and attenuation of esophageal inflammation in animal models (11)

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increase by ~50 mcg every 12 weeks as tolerated