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Orthologs of the genes encoding the ligands ( GCG, GIP ), their receptors ( GLP-1R, GIPR ) and DPP-4 have been identified in a range of vertebrate species (reviewed in refs 8, 9, 10)

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When dogs are on restricted dietswhether for weight loss, allergies, or medical managementnutrient adequacy can become more delicate, which is why monitoring is emphasized in energy restriction contexts (German AJ, 2015)

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