For some patients that is easier to live with
Established cardiovascular disease
The STEP 1 trial (Wilding et al., 2021), one of the largest studies on semaglutide, found that 39% of the weight lost over 68 weeks was lean mass
Common short-term effects include: Nausea after meals Vomiting, especially after large or oily meals Loose stools or diarrhoea Constipation Abdominal discomfort Reduced hunger Early fullness Mild headache Tiredness Dizziness Low blood sugar, mainly in people with diabetes who also take insulin or sulfonylurea medicines Dehydration if vomiting or diarrhoea is frequent Food aversions or dislike for certain smells Mild symptoms can often be managed with diet changes and hydration
Address potential side effects, so you understand what is common, what might be uncomfortable, and what would warrant medical attention
They provide the raw materials but dont amplify the signal, protect the hormones from breaking down, or address the other metabolic challenges that make weight loss difficult to sustain
