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The paper established MOTS-c as an "exercise mimetic" and launched the field of mitochondrial-derived peptide research (Lee C et al., Cell Metab
Its core mechanisms are closely related to disorders of cellular energy metabolism, accumulation of oxidative stress, and reduced capacity for DNA damage repair
High doses of vitamin C injections seem to have few side effects
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This covers the spectrum from chronic tendon degeneration to partial-thickness tears
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