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Business Strategies and Development 11.3.5

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Metabolic effects through IGF-1 receptor pathways

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In DKD, factors such as hyperglycemia and OS activate NF-B, which translocates from the cytoplasm to the nucleus

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demonstrated that erythrocytes possess Fas, FasL, FADD, showing that erythrocytes could form the DISC downstream of which caspase-8 and caspase-3 were activated [136]

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Supplementing with Arg can improve the overall transportation of Arg within cells and increase the bioavailability of endothelial NO, resulting in reduced blood pressure [53]

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Normal distribution was tested, and data was analysed using one-way analysis of variance (ANOVA) multiple comparisons or by the KruskalWallis non-parametric test

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