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We also discussed CMS' authority under section 1886(d)(4) of the Act to assign and update MS-DRG weighting factors to reflect relative resource use

Generally, mitochondrial respiration control, including oxygen consumption rate (OCR) and respiratory control ratio (RCR), is utilized to measure the mitochondrial function in diverse cell populations (Javadov et al., 2006, 2009)

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For a 250 mcg dose, this requires drawing 0.1 mL (10 units on an insulin syringe) of the reconstituted solution