Low carnitine status is generally due to impaired mitochondrial energy metabolism or to carnitine not being efficiently reabsorbed by the kidneys
The most common adverse reactions resulting in discontinuation were fatigue and thrombocytopenia (0.9% each)
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Symptoms of toxicity include tremors, confusion, nausea, and irregular heartbeat
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In chronic CCl4/HFD-induced liver injury, HSYA ameliorated serum biochemical indicator, reduced mRNA expression levels of pro-fibrotic factors and elevated hepatoprotective factors, which revealing that PPAR- and p38 MAPK signaling play pivotal roles in the prevention of liver fibrosis (Liu et al., 2014)