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The gut microbiota produces an array of bioactive metabolites, such as short-chain fatty acids (SCFAs), neurotransmitter precursors, and uremic toxins, that mediate communication between the gut, brain, and kidneys (Lin et al., 2025)

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His team tracked 7,938 adult patients in Ohio and Florida who had started injectable semaglutide or tirzepatide and then stopped the medication between three and twelve months after beginning treatment

Reassess after 812 weeks

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