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April 2025, Northstrive Biosciences In semaglutide to reduce the risk of serious heart problems in obese or overweight adults, and semaglutide becomes the first we igh58 t loss drug approved in the UK as a preventative treatment for those with established cardiovascular disease

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According to Sarwer and Maccarone, scientists believe these shifts in mood are caused by how the drug changes the brain's central reward pathways by diminishing responses to the neurotransmitter dopamine