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Rao S, Yao Y, Bauer DE
dose-finding studies) and commercial ambitions as part of a lifecycle management programme, both of which help to accelerate time to market
It was FDA-approved for Type 2 diabetes, and physicians frequently prescribe it off-label for weight management as well
Clinical Studies 14.1 Weight Reduction and Long-Term Maintenance Studies in Adults with Obesity or Overweight Weight Reduction in Adults with Obesity or Overweight, with or without Type 2 Diabetes Mellitus (Study 1 and Study 2) Overview of Study 1 and Study 2 The efficacy of ZEPBOUND for weight reduction in conjunction with a reduced-calorie diet and increased physical activity was studied in two randomized, double-blind, placebo-controlled fixed-dosage trials (Study 1 and Study 2) in adults aged 18 years and older
Some clinical experts and recent Phase 3 reporting have also noted that weight loss in some participants has been substantial enough to raise questions about how much weight loss may be too much, particularly when these medications are used outside tightly controlled medical settings and without provider supervision
Instead of offering a one-size-fits-all solution, each patient receives a tailored plan designed to support their body, lifestyle, and goals
