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G., Powell K

Brown adipose tissue dysfunction promotes heart failure via a trimethylamine N-oxide-dependent mechanism

However, a 2003 systematic review highlighted differences in methodologies between early and later studies that make it difficult to compare results (104)

Bacterial cells were collected by centrifugation at 4,000 g for 20 min at 4 C and the cell pellet was resuspended in buffer (50 mM NaH 2 PO 4 and 300 mM NaCl, pH 6.0)

It is naturally produced in the human body and can also be obtained through the diet, particularly through red meat and dairy products