Hepatic glutathione is essential for Phase II conjugation reactions that detoxify drugs, environmental pollutants, heavy metals, and endogenous waste products [6]
the composite GI adverse event rate across any GI symptom reached approximately 80% [2]
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It requires prescribers to extend the treatment conversation beyond the pharmacology
In summary, STAT3 is not only a central hub in pathological processes but also a key therapeutic target for alleviating disease progression through multiple pathways (e.g., inhibiting oxidative stress and regulating iron metabolism)