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1 Introduction Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease characterized primarily by chronic inflammation and progressive destruction of the joint synovium, often resulting in joint deformity and functional disability, significantly impairing patients quality of life ( In recent years, the roles of gut microbiota and ferroptosis in RA have gradually attracted attention

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2.3 Interaction of GIP and GLP-1 in the incretin effect Studies in rodents (46) and canines (47) have delineated the existence of a proximal-distal incretin loop

The effect of periodic ketogenic diet on newly diagnosed overweight or obese patients with type 2 diabetes