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MRTF family The mechano-sensitive myocardin family of transcriptional co-activators comprising myocardin, MRTF-A/MKL1/MAL, and MRTF-B/MKL2 are associated with the MADS box transcription factor SRF (serum response factor) to activate transcription of genes responsible for myogenesis, cell proliferation, migration and creation of transcriptionalcytoskeletal regulatory circuit by encoding components of actin cytoskeleton

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