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At the same time, the unfolded peptides can aggregate, forming clumps of misfolded protein

A positive feedback loop of ER-36/EGFR promotes malignant growth of ER-negative breast cancer cells

IUBMB life 60 , 790797, doi: 10.1002/iub.124 (2008)

According to the NHS, priapism commonly impacts people with sickle cell disease, but taking certain medications or illegal substances can also trigger it

Therefore, the protective activity of GSH is two-fold it enhances the activity of immune cells and functions as an antioxidant within them

Lower glutathione peroxidase activity weakens the brain's ability to clear hydrogen peroxide and lipid peroxides, promoting reactive oxygen species accumulation and oxidative stress, which ultimately damages neurons (108, 109)