and polyphenols, vitamins, and selenium
This device delivers electrical stimulation to the tongue muscles to stabilize airway patency
Psychopharmacology (Berl.) 150 , 325336 (2000)
Agents such as PT-141 or kisspeptin delivered centrally induce acute changes in desire within hours to days
This mechanism is why slow-release carbohydrates and prebiotic fibers are increasingly positioned to raise endogenous GLP-1 and PYY as a non-drug route to appetite regulation
This is about saving hearts Who qualifies: Adults with established CVD + overweight/obesity (BMI 27 kg/m) The drug: Semaglutide 2.4mg once-weekly subcutaneous injection (GLP-1 RA) Titrated to maintenance dose Adjunct to lifestyle counselling & standard care Why NICE said yes: Reduces risk of MACE (heart attack, stroke, CV death) in this population Cost-effective within NHS thresholds (20,00030,000/QALY) Commercial agreement already in place with NHS The pathway is simple: Assess CVD risk Lifestyle counselling Add semaglutide Monitor This follows SELECT trial data showing ~20% MACE reduction independent of weight loss We are watching GLP-1s redefine cardiovascular medicine in real time From diabetes obesity now primary CV risk reduction Whats next
