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The experimental protocol was approved by the Institutional Animal Care and Use Committee of Jining Medical University (Approval No

Falanga AP, Melone P, Cagliani R, Borbone N, DErrico S, Piccialli G, et al

(n.d.).

Neural degeneration might be associated with a widespread TDP-43 proteinopathy that contributes to the clinical manifestations of recurrent TBI, such as cognitive and memory loss, behavioral changes, and motor dysfunction