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Due to the lack of statistical significance for this initial key secondary endpoint in the hierarchical testing, all subsequent secondary endpoint analyses are described without statistical significance, providing nominal p-values

Phenobarbital is a prototypical xenobiotic that acts through the CAR receptor

Int J Endocrinol (2018) 2018:6920620

This becomes even more important since many off-label users get less monitoring than diabetic patients

Some individuals experience significant benefits at 10 mg or lower, with excellent tolerability and sustainable lifestyle integration