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doi:10.1056/NEJMoa2301972 2

No clinical trial has formally tested the retatrutide + cagrilintide combination as of May 2026

Diagnostic tools will sometimes overlap

Common Semalix 0.25 mg 0.5 mg pre-filled pen side effects are: Nausea or vomiting Diarrhea or constipation Abdominal pain or indigestion Reduced appetite or headache Mild injection-site reactions (redness, pain, swelling) If any of these side effects become severe or persistent, seek medical advice without delay