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For instance, clinical studies demonstrate that FMT can improve microbiota diversity, reduce complications such as hepatic encephalopathy and ascites, and significantly enhance survival in patients with AH 175,176,177,178

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Furthermore, miR-122 silencing in high-fat-fed mice reduced hepatic steatosis, with a decrease in cholesterol synthesis and stimulation of FAO 85

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Thus, uncovering these facts and findings could help explain the largely varying response amongst COVID-19 patients with the disease ranging from mild and symptomless to severe infections requiring hospitalization in some cases that often result in death