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Furthermore, removal of the methylene carboxy group at the C-terminal of 23 resulted in a less efficient IRAP inhibitor

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Both need to be kept at -20C 5C, but Cagrilintide is a little more sensitive to freeze-thaw cycles because of its molecular weight and disulfide bridges

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Furthermore, we validated that Dutasteride, an SRD5A1 inhibitor, induced myeloma cells apoptosis in human myeloma cells and xenograft mouse models