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Discussion Endothelial dysfunction can be considered as a valuable biomarker for predicting atherosclerosis and other cardiovascular lesions 10

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Although the benefits of GLP-1 RAs in HF (particularly HFrEF) and CAD remain less definitive, emerging data suggest potential roles in improving PAD and blood pressures, reducing symptoms in HF, and possibly lowering the risk of AF

However, as we embark on a weight management journey, it's crucial to consider the long-term efficacy and sustainability of these treatments

As both type 1 and 2 diabetes are associated with reduction of functional cells, this effect is desirable in diabetes treatment

Diabetes Care 36 , 10671073 (2013)