Reference: Schijns W, Homan J, van der Meer L, Janssen IMC, van Laarhoven CJHM, Berends FJ, Aarts EO
The shelf life varies by specific product, and all medications should be used before the expiration date printed on the packaging when stored according to the manufacturer's instructions: Semaglutide (Ozempic, Wegovy) : Unopened pens may be stored in the refrigerator until the expiration date on the label Dulaglutide (Trulicity) : Remains stable when refrigerated until the printed expiration date Liraglutide (Victoza, Saxenda) : Maintains potency when refrigerated continuously until expiration Tirzepatide (Mounjaro, Zepbound) : Stable under refrigeration until the manufacturer's expiration date Exenatide (Byetta, Bydureon BCise) : Requires refrigeration and remains effective until expiration when stored properly It is important to note that permitted room-temperature storage periods as specified in the prescribing information do not invalidate the expiration date
April 2026 Category 2 Update On April 15, 2026, the FDA confirmed removal of injectable GHK-Cu from Category 2 because the original nominations were withdrawn
Key findings of the paper: Finding 1: NNMT is highly expressed in adipose tissue
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