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Ashwagandha may work by interacting with components of the proinflammatory cell signaling pathway, such as NF-B, signaling kinases, HSP90, Nrf2, and the inflammasome complex, even though the mechanisms behind the anti-inflammatory effect of withanolides are not fully understood (71)

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Matrix Biol 68:827 Hellerbrand C, Stefanovic B, Giordano F, Burchardt ER, Brenner DA (1999) The role of TGF1 in initiating hepatic stellate cell activation in vivo

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