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Cravings become difficult to manage

Of note, in the recent consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD), the use of GLP-1RAs with proven cardiovascular benefits should be preferred for patients with type 2 diabetes who have established atherosclerotic cardiovascular disease or indicators of high risk

Another example is Erythropoietin, a hormone that promotes red blood cell production, which has been shown to protect cells from oxidative stress under low oxygen conditions [528, 529]

Most patients need long-term treatment to maintain weight loss

Key Success Factors: Motivation and Commitment: Successful participants are those committed to making sustainable lifestyle changes, including dietary adjustments and increased physical activity, as part of their weight management journey