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The pressure at your lower esophageal sphincter naturally decreases when you are in a supine, or horizontal position

However, levels are much lower compared to animal sources

Laughton Macallum

Changes in food, bodily functions, and the immune system produce a range of signals from microbial metabolites and their receptors

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Es decir, estamos ante una sustancia que nuestro organismo genera por s mismo de forma natural, como ocurre con otros muchos suplementos