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Comparing DSIP with Epitalon and Orexin clarifies its role as a tool for investigating integrated neuroendocrine signaling, sleep architecture, and pathway-level interactions in experimental systems

doi:10.5152/TurkThoracJ.2018.18014

For intervention studies, the most informative designs will be those that pair such biomarkers with therapeutically timed treatment in human acinar, organoid, or ex vivo tissue platforms before progression to etiology-diverse in vivo models (96)

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