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Postsynaptic density-95 mimics and occludes hippocampal long-term potentiation and enhances long-term depression

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ICC generate slow waves that control smooth muscle contractility, are involved in aspects of neurotransmission, set the smooth muscle membrane potential gradient and are involved in mechanotransduction as shown in Fig

Its sequence incorporates several amino-acid substitutions and an intramolecular disulfide bridge between two cysteine residues, together with a lipidation (fatty-acid acylation) modification that promotes reversible binding to serum albumin

Cirrhosis is the pathological replacement of functional liver tissue with scarred, fibrous, dysfunctional tissue, which can affect many of the livers metabolic processes and present a serious health threat

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