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Artemisinin blocks prostate cancer growth and cell cycle progression by disrupting Sp1 interactions with the cyclin-dependent kinase-4 (CDK4) promoter and inhibiting CDK4 gene expression

Financial support and sponsorship This work was supported by Japan Society for the Promotion of Science, Japan (Grant Number: 23K08806)

doi: 10.1016/j.biopha.2020.110857 178 ZhaoY.ZhangX

The general formula of a carboxylic acid is RCOOH, with R referring to the rest of the molecule

It is likely that overall changes in constitutive activity, in the absence of ghrelin, provide sufficient modulation of signaling pathways to demonstrate an important physiological effect

Zhang Y, Swanda RV, Nie L, Liu X, Wang C, Lee H, et al