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In addition, it significantly increased microbial diversity and altered their function, contributing to the treatment of hyperuricemic rats (Zhang et al., 2020)

Below is a list of GLP-1 medications available when this article was written: Dulaglutide (Trulicity): A once-weekly injectable medication that helps lower blood sugar levels and promote weight loss

NICE guidance (NG28) recommends considering GLP-1 receptor agonists for adults with type 2 diabetes when glycaemic targets are not achieved with other therapies, particularly in those with established cardiovascular disease or at high cardiovascular risk

The exact mechanism for topiramates weight effect is still partly understood, but the clinical results are well documented