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It has documented side effects, including nausea, diarrhoea, constipation and abdominal pain

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Safety considerations include GLP-1 contraindications (personal or family history of medullary thyroid cancer, multiple endocrine neoplasia type 2, severe pancreatitis risk, pregnancy)

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Bovee-Oudenhoven IM, ten Bruggencate SJ, Lettink-Wissink ML, Meer van der R: Dietary fructo-oligosaccharides and lactulose inhibit intestinal colonisation but stimulate translocation of salmonella in rats